I-Rheumatoid Arthritis (RA) sisifo esinganyangekiyo samalungu. Ngaphakathi emzimbeni, amalungu ngamanqaku apho amathambo ahlanganisana kunye kwaye avumele intshukumo. Uninzi lwala malungu - abo babizwa ngokuba ngamalungu e-connovial-kubonelela ngokufuduka kothukile.
I-RA yimeko ye-Autimmuune, apho amajoni akho anempazamo kangakanani na iimpazamo zamalungu akho angenayo 'kwaye 'ungaphandle ' nohlaselo kwaye zibachaphazele, zibangelwa kukuvuvukala kunye nentlungu.
Esi sifo sihlala sichaphazela udibano lwezandla, ii-Wrists, kunye namadolo alinganayo. Akukho nyango, kodwa i-R ayinakulawulwa ngonyango olulungileyo, ngokweeMaziko lolawulo lwezifo kunye nothintelo (i-CDC).
Iimpawu kunye neempawu ze-rafuumatoid Arthritis
Isifo samathambo sisifo sisifo esinzima esingaqondwa kakuhle ngabagqirha okanye abaphandi.
Iimpawu zakuqala zesifo, njengokudumba, iintlungu ezidibeneyo, kunye nokuqina okuqinileyo, ngokwesiqhelo ziqala kancinci kancinci kwiiveki eziziinyanga kwaye zisiba mandundu kakhulu. Ra ihlala iqala kumathambo amancinci ezandla (ngakumbi abo basesiseko kwaye embindini weminwe), isiseko seenzwane, kunye namaqhinga. Ukuqina kwentsasa ehlala ihlala imizuzu engama-30 okanye nangaphezulu yenye into ephawulayo ye-ra, ngokwesiseko se-Arthris.
IRa sisisifo esinenkqubela phambili. Xa ushiywe unganyangwa, ukuvuvukala kunokuqala ukukhula kwezinye iindawo zomzimba, kubangela iingxaki ezahlukeneyo ezinokubangela amanye amalungu, ezinjengentliziyo, kwaye kunokubangela ukukhubazeka kwexesha elide.
Ukuba uhlangabezana neempawu ze-R, kubalulekile ukuba ufunyaniswe ngokukhawuleza ukuze ufumane unyango ngokukhawuleza.
Unobangela kunye nezixhobo zomngcipheko ze-rheumatoid Arthritis
I-RA ikhula xa iiseli ezimhlophe zegazi, eziqhelekileyo zikhusela umzimba kwiintsana zangaphandle ezinje ngebhaktiriya nakwintsholongwane, zingena kwi-synovium (izicubu ezicekeceke). Ukuvuvukala okwenzayo - i-synovium riyens, iyenza ukudumba, ibomvu, ifudumele, kunye nentlungu kwintshukumo yentsingiselo.
Ixesha elingaphezulu, i-synovium ye-inflemen inokuyonakalisa i-cartilage kunye nethambo ngaphakathi kwehlazo, kunye neesihlunu ezixhasayo, i-ligaments, kunye neetekisi.
Abaphandi abazi ngqo ukuba yintoni ebangela amajoni omzimba ahlasele i-synovium, kodwa kukholelwa ukuba iimfuza kunye nezinto zokusingqongileyo zidlala indima ekuphuhlisweni kweRA.
Uphando lubonisa ukuba abantu abaneemfuza ezithile, abangumntu eLeukocyte Antigen (HLA) imfuza, bakhule kakhulu emngciphekweni wokuphuhlisa i-ra. I-HLA ye-HLA ye-GLA ye-GLA ye-GLA yomzimba ofanelekileyo ngokufaka iiproteni ezinceda amajoni omzimba aqonde iiprotein kubahlaseli bamanye amazwe.
Inani lezinye iintlobo zibonakala zinxulunyaniswa ne-Ratineceffantle, kubandakanya i-Atta4, PTPN22, PTPN2-C5, Padi4, Ctla4, i-TTLA4, phakathi kwengxelo yejenali Rheumatology.
Kodwa ayinguye wonke umntu onazo ezi zahlukile ze-gene echongiweyo i-ra, kwaye abantu ngaphandle kwabo basenokuyiphuhlisa. Ke, kunokwenzeka ukuba izinto zokusingqongileyo zihlala zibangela isifo, ngakumbi kubantu abane-makepe yemfuza ebangela ukuba babethathwe ngakumbi kuyo. Ezi zinto zibandakanya:
Intsholongwane kunye neBacteria (nangona usulelo oluthile lungawunciphisa umngcipheko, ubuncinci okwethutyana)
I-hormones ye-hormones
Ukuvezwa kweentlobo ezithile zothuli kunye neentsinga
Ukuvezwa komsi we-terhand
Ukutyeba, okwandisa ukuqhubela phambili kokukhubazeka kwabantu abane-RA. Izigulana ezityebileyo zinokubangela ukuba zifezekise uxolelo lweRara ngaphandle kokuba bafumane impatho.
Iziganeko ezixinzelelekileyo
Ukutya
Eyona nto ibaluleke kakhulu kukutshaya kunye nembali yosapho yeRA ekwandisa umngcipheko wokuphuhlisa imeko.
Abantwana ukuya kuthi ga kwiminyaka eli-16 enamava avuthiweyo okanye udibaniselwano olubuhlungu naphi na emzimbeni bahlala benesifo se-idiopatic arthritis (JIA).
Ifunyaniswa njani iRheumaid Arthritis?
Ngelixa kungekho luvavanyo olunye lungafumanisa ngokucacileyo i-ra, ogqirha baqwalasela izinto ezininzi xa bevavanya umntu ukuba abe ne-Rheumad Arthritis.
Inkqubo yokuqonda isifo iqala xa ugqirha efumana imbali yakho yezonyango kwaye wenza uvavanyo lomzimba. Baza kukucela malunga neempawu zakho ukukhangela iimpawu zeRA, kwizinto ezithile ezifana nokuhamba ixesha elide ngokudumba kunye nokuqina kwentsasa ehlala ihamba iyure emva kokuba uvuke.
Emva koko, ugqirha wakho uya ku-odola uvavanyo lwegazi ukuba abone into ye-Rheumatoid (i-RF) kunye nee-antin zeprotein zeproteyini zeProtein (i-ACPAS), ezinokubakho i-ra. Usenokuba ne-Artitical Andtimitis ye-Idormaticary kunye okanye ngaphandle kwamagosa ahambahambayo.
Ukucingisisa uvavanyo olunjenge-X-ray, i-ultrasound, kunye ne-magnetic scans scans inokusetyenziselwa ukuba ugqirha uqinisekisiwe okanye ukufumanisa ukungcola kwe-incossion, ukhukuliseko oludibeneyo.
Kwixa elizayo, oogqirha banokukwazi ukufumanisa i-RAPONOS ROST (NOROVVA)
Iindidi ezahlukeneyo zesifo samathambo seRheumatoid
I-Rheumatoid Arthritis ihlelwe njengeyona ndlela ye-seropotive okanye i-seroneive.
Abantu abane-rapofectist Ra i-ACDAS, bakwabizwa ngokuba yi-Anti-Cyclicated i-Pittides peptides, efumaneka kuvavanyo lwegazi labo. Ezi antibodies zihlasela amalungu onxibelelaniso kwaye zivelise iimpawu zeRA.
Malunga ne-60 ukuya kwi-80 pesenti yabantu abafunyaniswayo nge-ACPPAs, kwaye kubantu abaninzi, ii-antibodies zahlula iimpawu ze-RA kwiminyaka emi-5 ukuya kweli-10, zitsho isiseko se-Arthritis.
Abantu abane-seronegive Ra banesifo ngaphandle kobukho bee-antibodies okanye i-RF egazini labo.
Ixesha leRheumatoid Arthritis
I-RA sisifo esiqhubayo nesingapheliyo. Umonakalo kumathambo adibeneyo wenzeka kwangoko kakhulu ekuqhubeni kwesi sifo, ngokuqhelekileyo kwiminyaka emibini, ngokwendlela ye-Johns Hopkins Arthritis. Kungenxa yoko le nto unyango lwakwangoko lubaluleke kangaka.
Ngonyango olusebenzayo, lwangaphambi kwexesha, uninzi lwabantu olune-Ra banokuphila ngendlela abaqhele ngayo, kwaye abantu abaninzi banokufumana ukuxolelwa kwiimpawu. Oku akuthethi ukuba ukhuselekile kodwa kunokuba iimpawu zakho ziphethwe kwindawo apho unokusebenza khona kwinqaku elifanelekileyo kwaye amalungu akho angonakaliswa ngakumbi yiRA. Inakho ukufezekisa ukuxolelwa kwaye emva koko uphinde uphinde uphinde ubuyele.
Kodwa akuzange kwenzeke wonke umntu, kwaye ngenxa yokuba iintlungu kunye nezinye iimpawu zeRA zinokutshintsha ngokuhamba kwexesha, ulawulo lweentlungu lunokuba yinkxalabo eqhubekayo. Ukongeza kumayeza eentlungu afana ne-nonsteroidal anti-i-insmmaridal anti-i-ivorammary kunye ne-corticosteroids, zininzi iindlela zokukhululeka kwentlungu kubantu abahlala neRA. Oku kubandakanya, phakathi kwezinye:
Izongezo zeoyile zeoyile
Unyango olushushu nolubandayo
Ukuzivocavoca kunye nentshukumo
Izinto ezingafunekiyo zomzimba ezifana nokuncitshiswa okusekwe kwingqondo kunye nokwamkelwa kunye nokuzibophelela unyango
I-Biofeedback
