Rheumatoid arthritis (RA) chirwere chisingaperi chinoputira majoini.Mukati memuviri, majoini ndiwo mapoinzi apo mapfupa anouya pamwe chete uye anobvumira kufamba.Mazhinji emajoini aya - ayo anonzi ma synovial joints - anopawo kubatwa kwekuvhunduka.
RA ndeye autoimmune mamiriro, umo immune system yako inokanganisa marara emajoini ako se 'mutorwa' uye anorwisa nekuakuvadza, zvichikonzera kuzvimba nekurwadziwa.
Chirwere ichi chinowanzobata majoini emaoko, mawoko, nemabvi zvakaenzanirana.Iko hakuna mushonga, asi RA inogona kutarisirwa nekurapa kwakanaka, maererano neCenters for Disease Control and Prevention (CDC).
Zviratidzo uye Zviratidzo zveRheumatoid Arthritis
Rheumatoid arthritis chirwere chakaoma chisinganyatsonzwisiswi nevarapi vezvokurapa kana vatsvakurudzi.
Zviratidzo zvekutanga zvechirwere, zvakadai sekuzvimba kwemajoini, kurwadziwa kwemajoini, uye kuoma kwemajoini, kazhinji zvinotanga zvishoma nezvishoma uye zvisingatarisirwi, uye zviratidzo zvinokura zvishoma nezvishoma kwemavhiki kusvika kumwedzi uye zvichiwedzera nekufamba kwenguva.RA inowanzotanga mumapfupa maduku emaoko (kunyanya ayo ari pasi nepakati peminwe), nheyo yezvigunwe, uye mawoko.Kuoma kwemangwanani kunotora maminetsi makumi matatu kana kupfuura chimwe chiratidzo cheRA, maererano neArthritis Foundation.
RA chirwere chinopfuurira.Kana ikasarapwa, kuzvimba kunogona kutanga kukura mune dzimwe nzvimbo dzemuviri, zvichikonzera matambudziko akakura anogona kukanganisa dzimwe nhengo, semoyo, mapapu, uye tsinga, uye zvinogona kukonzera kuremara kwenguva refu.
Kana uri kuona zviratidzo zveRA, zvakakosha kuti uongororwe nekukurumidza kuitira kuti ugone kurapwa nekukurumidza.
Zvinokonzera uye Njodzi Zvikonzero zveRheumatoid Arthritis
RA inokura apo masero machena eropa, ayo anowanzo dzivirira muviri kubva kune dzimwe nyika dzinopinda munyika dzakadai sebhakitiriya nemavhairasi, inopinda mu synovium (tishu yakatetepa inotenderera synovial joints).Kuzvimba kunotevera - iyo synovium inokora, ichikonzera kuzvimba, kutsvuka, kudziya, uye kurwadziwa mu synovial joint.
Nokufamba kwenguva, iyo inoputika synovium inogona kukuvadza cartilage uye pfupa mukati mejoinhi, pamwe nekunetesa mhasuru dzinotsigira, ligaments, uye tendon.
Vatsvakurudzi havazivi chaizvo kuti chii chinoita kuti immune system ipinde mu synovium, asi zvinotendwa kuti majini uye zvakatipoteredza zvinoita basa mukuvandudza RA.
Tsvagiridzo inoratidza kuti vanhu vane mamwe genetics, iyo yemunhu leukocyte antigen (HLA) majini, vane njodzi yakawedzera yekuvandudza RA.Iyo HLA gene complex inodzora mhinduro dzemuviri nekugadzira mapuroteni anobatsira immune system kuziva mapuroteni kubva kune vatorwa.
Mamwe majini akati wandei anoita seane hukama neRA susceptibility, kusanganisira STAT4, PTPN22, TRAF1-C5, PADI4, CTLA4, pakati pevamwe, maererano neshumo mumagazini Rheumatology.
Asi havasi vese vane mageneti aya akasiyaniswa anovaka RA, uye vanhu vasina ivo vanogona kuigadzira.Saka, zvingangoita kuti zvakatipoteredza zvinowanzokonzera chirwere, kunyanya muvanhu vane genetic makeup inoita kuti vanyanye kubatwa nayo.Zvinhu izvi zvinosanganisira:
Mavhairasi uye mabhakitiriya (kunyangwe humwe hutachiona hunogona kuderedza njodzi yeRA, kwechinguvana)
Mahomoni echikadzi
Kuratidzwa kune mamwe marudzi ehuruva nemafiibha
Kusvuta fodya
Kufutisa, izvo zvinowedzerawo kufambira mberi kwekuremara kune vanhu vane RA.Varwere vakafutisa kashoma kuti vawane kuregererwa kweRA zvisinei nekurapwa kwavanoitwa.
Zviitiko zvinoshungurudza zvakanyanya
Zvokudya
Zvinokosha zvakaenzana kusvuta uye nhoroondo yemhuri yeRA mukuwedzera njodzi yemunhu yekukudziridza chimiro.
Vana vanosvika pazera re16 vanosangana nekuzvimba kwenguva refu kana kurwadza majoini chero kupi mumuviri vanowanzoonekwa vaine juvenile idiopathic arthritis (JIA).
Rheumatoid Arthritis Inowanikwa Sei?
Kunyange pasina bvunzo imwe chete inogona kunyatso ongorora RA, vanachiremba vanofunga zvinhu zvakati kuti pavanenge vachiongorora munhu kuti ane rheumatoid arthritis.
Nzira yekuongorora inowanzotanga apo chiremba anotora nhoroondo yako yezvehutano uye anoongorora muviri.Vachakubvunza nezvezviratidzo zvako kuti utarise zviratidzo zveRA, kunyanya zvinhu zvakaita sekuzvimba kwemajoini kwenguva refu uye kuoma kwemangwanani kunotora hafu yeawa mushure mekunge wamuka.
Zvadaro, chiremba wako acharayira kuongororwa ropa kuti aone rheumatoid factor (RF) uye anti-citrullinated protein antibodies (ACPAs), inogona kuva zviratidzo zveRA uye zvinogona kuratidza RA.Iwe unogona kuramba uine symmetrical kuzvimba arthritis ine kana isina systemic mamaki ekuzvimba.
Imaging bvunzo dzakadai seX-ray, ultrasound, uye magineti resonance imagery scans inogona kushandiswa kubatsira chiremba kuona kana majoini ako akakuvadzwa kana kuona kuzvimba kwemajoini, kukukurwa, uye kuwanda kwemvura.
Mune ramangwana, vanachiremba vanogona kukwanisa kuongorora RA vachishandisa (noninvasive) infrared light.
Mhando dzakasiyana dzeRheumatoid Arthritis
Rheumatoid arthritis inorondedzerwa se seropositive kana seronegative.
Vanhu vane seropositive RA vane ACPAs, inonziwo anti-cyclic citrullinated peptides, inowanikwa mukuongororwa kweropa ravo.Aya masoja ekudzivirira chirwere anorwisa synovial joints uye anoburitsa zviratidzo zveRA.
Inenge 60 kusvika ku80 muzana yevanhu vakaonekwa kuti vane RA vane ACPAs, uye kuvanhu vakawanda, masoja ekudzivirira chirwere anotangira zviratidzo zveRA nemakore mashanu kusvika ku10, inodaro Arthritis Foundation.
Vanhu vane seronegative RA vane chirwere pasina kuvapo masoja ekudzivirira chirwere kana RF muropa ravo.
Nguva yeRheumatoid Arthritis
RA chirwere chinopfuurira uye chisingaperi.Kukuvadzwa kwemapfupa akabatanidzwa kunoitika pakutanga kwechirwere, kazhinji mukati memakore maviri ekutanga, maererano neJohns Hopkins Arthritis Center.Ndosaka kurapwa kwekutanga kwakakosha.
Nekurapwa kunoshanda, kwekutanga, vanhu vazhinji vane RA vanogona kurarama sezvavanowanzoita, uye vanhu vazhinji vanogona kuwana kuregererwa kwezviratidzo.Izvi hazvireve kuti wapora asi kuti zviratidzo zvako zvinorerutswa kusvika paunokwanisa kushanda zvakakwana uye majoini ako haasi kuwedzera kukuvadzwa neRA.Zvinogonekawo kuwana kuregererwa uye wobva wadzokera, kana kuti zviratidzo zvako zvidzoke.
Asi kuregererwa hakuitike kune wese munhu, uye nekuti marwadzo nezvimwe zviratidzo zveRA zvinogona kushanduka nekufamba kwenguva, kutonga kwemarwadzo kunogona kuve kunetseka kunoenderera.Pamusoro pemishonga yemarwadzo senge nonsteroidal anti-inflammatory drugs uye corticosteroids, pane zvakawanda zvingasarudzwa zvekuzorodza marwadzo kuvanhu vanogara neRA.Izvi zvinosanganisira, pakati pezvimwe:
Mafuta ehove anowedzera
Mishonga inopisa uye inotonhora
Kudzidzira muviri uye kufamba
Mind-body modalities senge mindfulness-based stress kuderedza uye kubvuma uye kuzvipira kurapa
Biofeedback
